Transcriptomic drug-response gene signatures are informative for the stratification of patients for clinical trials

Key words

Asthma is a chronic heterogeneous inflammatory disorder of the airways with mixed lymphocytic and myelogenous infiltrates. Cellular characterization of this disorder has identified 4 phenotypes: eosinophilic (T2), neutrophilic (T1), mixed eosinophilic/neutrophilic, and paucigranulocytic.

  • Simpson J.L.
  • Scott R.
  • Boyle M.J.
  • Gibson P.G.
Inflammatory subtypes in asthma: assessment and identification using induced sputum.