Two non-overlapping precursors generate Foxp3+ regulatory T cells in the thymus



https://1.bp.blogspot.com/-FEguRGgMDXE/XEe0ICFOJ4I/AAAAAAAAEJY/CkJSeiis29cBCpDhpKeGpVwC_ePLK1bbACLcBGAs/w1200-h630-p-k-no-nu/Screenshot%2B%25281751%2529.png

in summary, two types of thymic precursors can generate Tregs. Since their #TCR did not overlap with each other but both of them overlapped with mature #Foxp3+ #Tregs it suggests certain #functional bifurcation considering differences in protection against tissue #inflammation.





Source link